Abstract Background Manual annotation of enzymatic functions cannot keep up with automatic genome sequencing.In this work we explore the capacity of InterPro sequence signatures to automatically predict enzymatic function.Results We present EnzML, a multi-label classification method that can efficiently account also for proteins with multiple enzym

Eukaryotic chromosome segregation relies upon specific connections from DNA to the microtubule-based spindle that forms at cell division.The chromosomal locus that directs this process is the centromere, where a structure called the kinetochore forms upon entry into mitosis.Recent crystallography and single-particle electron microscopy have provide

Cannabis is the most commonly used illicit drug worldwide.Recently, cannabis use Accessories:Car among young pregnant women has greatly increased.However, prenatal cannabinoid exposure leads to long-lasting cognitive, motor, and behavioral deficits in the offspring and alterations in neural circuitry through various mechanisms.Although these effect

BackgroundRift Valley fever (RVF) is a vector-borne viral zoonosis of increasing global importance.RVF virus (RVFV) is transmitted either through exposure to infected animals or through bites from different species of infected mosquitoes, mainly of Aedes and Culex genera.These mosquitoes are very sensitive to environmental conditions, which may det